Chapter 3: Inheritance and Variation Balbharati Solutions for Biology 12th Standard HSC Maharashtra State Board

Chapter 3: Inheritance and Variation

Multiple choice question.

Phenotypic ratio of incomplete dominance in Mirabilis jalapa.

2 : 1 : 1

1 : 2 : 1

3 : 1

2 : 2


In a dihybrid cross, F2 generation offsprings show four different phenotypes while the genotypes are _______.

six

nine

eight

sixteen


A cross between an individual with an unknown genotype for a trait with recessive plant for that trait is _______.

back cross

reciprocal cross

monohybrid cross

test cross


When phenotypic and genotypic ratios are the same, then it is an example of _______.

incomplete dominance

complete dominance

multiple alleles

cytoplasmic inheritance


If the centromere is situated near the end of the chromosome, the chromosome is called ______.

metacentric

acrocentric

sub-metacentric

telocentric


Chromosomal theory of inheritance was proposed by _______.

Sutton and Boveri

Watson and Crick

Miller and Urey

Oparin and Halden


If the genes are located in a chromosome as p-q-r-s-t, which of the following gene pairs will have the least probability of being inherited together?

p and q

r and s

s and t

p and s


Find the mismatch pair:

Down’s syndrome = 44 + XY

Turner’s syndrome = 44 + XO

Klinefelter syndrome = 44 + XXY

Super female = 44 + XXX


A colour-blind man marries a woman, who is homozygous for normal colour vision, the probability of their son being colour blind is –

0%

25%

50%

100%


Very Short Answer Question.


Explain the statement of Test cross is back cross but back cross is not necessarily a test cross.

Solution: 

In back cross F1 generation can be crossed with either dominant or recessive parent.

But in test cross, F1 generation is crossed with a recessive parent only.

Thus, in the back cross, if F1 generation is crossed with a recessive parent it will be a test cross, but if F1 generation is crossed with a dominant parent it will not be a test cross. Therefore, the test cross is a back cross but the back cross is not necessarily a test cross.


Explain the statement of Law of dominance is not universal.

Solution: 


According to law of dominance, when two homozygous individuals with one or more sets of contrasting characters are crossed, the alleles (characters) that appear in F1 are dominant and those which do not appear in F1 are recessive.

In many cases, the dominance is not complete or absent. This can be explained by two deviations of Mendel’s law of dominance: Incomplete dominance and codominance. Thus, law of dominance is significant and true, but it is not universally applicable


Define the following:


Test cross.

Solution: 


Test cross: The cross between F1 hybrid and its homozygous recessive parent is called a test cross.


Homozygous

Solution: 


Homozygous - Diploid condition where both the alleles are identical is called homozygous.


Heterozygous

Solution: 


Heterozygous - Diploid condition where both the alleles are different is called heterozygous.


Very Short Answer Questions.


Define dihybrid cross

Solution: 


A cross between parents differing in two heritable traits is called a dihybrid cross.

OR

A cross between two pure (homozygous) parents in which the inheritance pattern of two pairs of contrasting characters is considered simultaneously is called a dihybrid cross.


What is allosome?

Solution: 


The chromosomes which are responsible for the determination of sex are known as Allosomes (sex chromosomes).


What is crossing over?

Solution: 


Crossing over is a process that produces new combinations (recombinations) of genes by interchanging and exchanging of corresponding segments between non-sister chromatids of homologous chromosomes.

It occurs during pachytene of prophase I of meiosis.

The mechanism of crossing over consists of four sequential steps such as synapsis, tetrad formation, crossing over, and terminalisation.

The phenomenon of crossing over is universal and it is necessary for the natural selection because it increases the chances of variation.


Give one example of the autosomal recessive disorder.

Solution: 


Autosomal recessive traits Phenyl ketonuria (PKU), Cystic fibrosis, and Sickle cell anaemia.


What are X-linked genes?

Solution: 


The genes which are present on the non-homologous region of X-chromosome are known as X-linked genes.


What are holandric traits?

Solution: 


The traits that are controlled by genes present only on the Y chromosome are known as holandric traits.


Give an example of a chromosomal disorder caused due to nondisjunction of autosomes.

Solution: 


Down syndrome is an example of a chromosomal disorder caused due to non-disjunction of autosomes.


Give one example of complete sex linkage?

Solution: 


Examples of X-linked traits are hemophilia, red-green colour blindness, myopia (near sightedness), and for Y-linked are hypertrichosis, ichthyosis, etc.


Enlist seven traits of pea plant selected/ studied by Mendel.

Solution: 


Following are the seven traits of pea plant selected/studied by Mendel:

Character

Contrasting form / traits

 

Dominant

Recessive

1. Height of stem

Tall

Dwarf

2. Colour of flower

Purple

White

3. Position of flower

Axial

Terminal

4. Pod shape

Inflated

Constricted

5. Pod colour

Green

Yellow

6. Seed shape

Round

Wrinkled

7. Seed colour (cotyledon)

Yellow

Green



Why law of segregation is also called the law of purity of gametes?

Solution: 


A diploid organism contains two factors for each trait in its diploid cells and the factors segregate during the formation of gametes.

The two alleles (contrasting characters) do not mix, alter or dilute each other and the gametes formed are ‘pure’ for the characters which they carry.

A gamete may carry either a dominant or recessive factor but not both.

Hence, this law is also called the law of purity of gametes.



Write a note on pleiotropy.

Solution: 


When a single gene controls two (or more) different traits it is called pleiotropic gene and the phenomenon is called pleiotropy or pleiotropism.

The phenotypic ratio is 1:2 instead of 3:1 because of the death of recessive homozygote. The disease, sickle-cell anaemia, is caused by a gene HbS.

Normal or healthy gene HbA is dominant. The carriers (heterozygotes HbA /HbS) show signs of mild anaemia as their RBCs become sickle shaped i.e. half-moon-shaped only under abnormally low O2 concentration.

The homozygotes with recessive gene HbS die of fatal anaemia.

Thus, the gene for sickle-cell anaemia is lethal in homozygous condition and produces sickle cell trait in the heterozygous carrier. Two different expressions are produced by a single gene.



What are the reasons for Mendel’s success?

Solution: 


Following are the reasons for Mendel’s success:

His experiments were carefully planned and involved a large sample.

He carefully recorded the number of plants of each type and expressed his results as ratios.

In the pea plant, contrasting characters can be easily recognized.

The seven different characters in the pea plant were controlled by a single factor each.

The factors are located on separate chromosomes and these factors are transmitted from generation to generation.



“Father is responsible for determination of sex of child and not the mother”. Justify.

Solution: 


A human male has 44 autosomes + XY sex chromosomes, whereas a female has 44 autosomes + XX sex chromosomes.

During gamete formation in male, the diploid germ cells in testis undergo spermatogenesis to produce two types of haploid sperms, 50% sperms contain 22 autosomes and X chromosome while 50% sperms contain 22 autosomes and Y chromosome.

In females, the diploid germ cells in ovaries undergo oogenesis to produce only one type of egg. All eggs contain 22 autosomes and the X chromosome.

Thus human male is heterogametic and female is homogametic.

If a sperm containing X chromosome fertilizes the egg (ovum), the diploid zygote formed after fertilization grows into a female child.

If a sperm containing Y chromosome fertilizes the egg, then diploid zygote formed after fertilization grows into a male child.

The sex of a child depends on the type of sperm fertilizing the egg and hence the father is responsible for the determination of sex of the child and not the mother

Chapter 3: Inheritance and Variation Balbharati Solutions for Biology 12th Standard HSC Maharashtra State Board


What is a linkage? How many linkage groups do occur in human being?

Solution: 


The tendency of two or more genes presents on the same chromosomes to be inherited together is known as linkage. The haploid number of chromosomes in humans is 23 therefore there are 23 linkage groups in humans.


Write note on –PKU.

Solution: 


Phenylketonuria is an inborn metabolic disorder caused due to deficiency of phenylalanine hydroxylase enzyme.

Phenylketonuria is caused due to recessive autosomal genes.

When recessive genes are present in homozygous condition, phenylalanine hydroxylase enzyme is not produced.

This enzyme is essential for the conversion of amino acid phenylalanine into tyrosine.

Due to the absence of this enzyme, phenylalanine is not converted into tyrosine.

Hence, phenylalanine and its derivatives are accumulated in blood and cerebrospinal fluid (CSF).

It affects development of the brain and causes mental retardation.

Excess phenylalanine is excreted in urine, hence this disease is called phenylketonuria.


Compare X chromosome and Y chromosome.


Solution: 


X Chromosome

Y Chromosome

1. It is metacentric, hence appears X shaped.

1. It is acrocentric, hence appears Y shaped

2. It is longer than ‘Y’ chromosomes.

2. It is shorter than ‘X’ chromosomes.

3. It contains a large amount of euchromatin and a small amount of heterochromatin.

3. It contains large amount of heterochromatin and small amount of euchromatin.

4. It is found in both males and females.

4. It is found only in males.

5. Non-homologous part of X chromosome shows more genes than Y chromosome.

5. Non-homologous part of Y chromosome contains few genes as compared to X chromosome.

6. X – linked genes are present on the X chromosome.

6. Y-linked genes (Holandric genes) are present on Y chromosome.

7. Genes present on X chromosome show crisscross inheritance.

7. Genes present on Y chromosome show straight inheritance.



Explain the chromosomal theory of inheritance.

Solution: 


The chromosomal theory of inheritance was proposed by Sutton and Boveri.

Following are the postulates of chromosomal theory of inheritance:

Chromosomes are found in pairs in somatic or diploid cells.

During gamete formation, homologous chromosomes pair, segregate and assort independently at meiosis. Due to this, each gamete contains only one chromosome of a pair.

Hereditary characters are carried by chromosomes which are present in the nucleus of these gametes.

Gametes (sperm and egg) contain all the hereditary characters. They form the link between parents and offsprings.

The union of sperm and egg during fertilization restores the diploid number of chromosomes.


Observe the given pedigree chart and answer the following question.

Chapter 3: Inheritance and Variation Balbharati Solutions for Biology 12th Standard HSC Maharashtra State Board

Identify whether the trait is sex-linked or autosomal.

Solution: 


The trait represented in given pedigree is sex linked trait.


Observe the given pedigree chart and answer the following question.

Chapter 3: Inheritance and Variation Balbharati Solutions for Biology 12th Standard HSC Maharashtra State Board

Give an example of a trait in human beings which shows such a pattern of inheritance.

Solution: 


Haemophilia, colour blindness are examples of sex-linked traits in humans.


Match the column-I with column-II and re-write the matching pairs.

Column-I

Column-II

1. 21 trisomy

a. Turner’s syndrome

2. X-monosomy

b. Klinefelter’s syndrome

3. Holandric traits

c. Down's syndrome

4. Feminized male

d. Hypertrichosis


Solution: 


Column-I

Column-II

1. 21 trisomy

c. Down's syndrome

2. X-monosomy

a. Turner’s syndrome

3. Holandric traits

d. Hypertrichosis

4. Feminized male

b. Klinefelter’s syndrome


Very Short Answer Questions.

Define dihybrid cross

Solution: 


A cross between parents differing in two heritable traits is called a dihybrid cross.

OR

A cross between two pure (homozygous) parents in which the inheritance pattern of two pairs of contrasting characters is considered simultaneously is called a dihybrid cross.



Long answer type question.


Explain a dihybrid cross with suitable example and checker board method.

Solution: 


The phenotypic ratio of different types of offsprings (with different combinations) obtained in F2 generation of dihybrid cross is called the dihybrid ratio. It is 9 : 3 : 3 : 1.

For example, when we cross a yellow round seed pea plant with a green wrinkled seed pea plant, we get 9 yellow round, 3 yellow wrinkled, 3 green round and 1 green wrinkled plants in the F2 generation.

Chapter 3: Inheritance and Variation Balbharati Solutions for Biology 12th Standard HSC Maharashtra State Board

 

Chapter 3: Inheritance and Variation Balbharati Solutions for Biology 12th Standard HSC Maharashtra State Board

Phenotypic ratio: Yellow round = 9 ;Yellow wrinkled = 3; Green round = 3; Green wrinkled = 1

Dihybrid ratio → 9 : 3 : 3 : 1

Genotypic ratio → 

YYRR YYRr YyRR YyRr YYrr Yyrr yyRR yyRr yyrr

  1   :   2    :   2   :   4   :   1  :  2  :   1   :  2  :   1



Explain with suitable examples an independent assortment.

Solution: 


Law of independent assortment:

The law states that, when a hybrid possessing two (or more) pairs of contrasting factors (alleles) forms gametes, the factors in each pair segregate independently of the other pair.

OR

The law of independent assortment states that, when two parents differing from each other in two or more pairs of contrasting characters are crossed, then the inheritance of one pair of character is independent of the other pair of character

1. This law is based on a dihybrid cross.

2. It describes how different genes or alleles present on separate chromosomes independently separate from each other, during the formation of gametes. These alleles are then randomly united in fertilization.

3. In dihybrid cross, F2 phenotypic ratio 9:3:3:1 indicates that the two pairs of characters behave independent of each other. It can be concluded that the two characters under consideration are assorted independently giving rise to different combinations.

Chapter 3: Inheritance and Variation Balbharati Solutions for Biology 12th Standard HSC Maharashtra State Board

Chapter 3: Inheritance and Variation Balbharati Solutions for Biology 12th Standard HSC Maharashtra State Board

Result: Tall red = 9; Tall white = 3; Dwarf red = 3; Dwarf white = 1

Phenotypic ratio → 9 : 3 : 3 : 1

Genotypic ratio → 

1 :  2  :  2  :  4  :  1  :  2  :  1  :  2  :  1

TTRR  TTRr  TtRR  TtRr  ttRR  ttRr  TTrr  Ttrr   ttrr

From the above results, it is obvious that the inheritance of character of tallness is not linked with the red colour of the flower. Similarly, the character of dwarfness is not linked with the white colour of the flower. This is due to the fact that in the above cross, the two pairs of characters segregate independently. In other words, there is an independent assortment of characters during inheritance.


Define test cross and explain its significance.

Solution: 


Definition:

The cross between F1 hybrid and its homozygous recessive parent is called a test cross.

Significance of test cross:

1. It helps to determine whether individuals exhibiting dominant character are genotypically homozygous or heterozygous.

2. It has wide application in plant breeding experiments.

3. In rapid crop improvement programmes, test cross is used to introduce a useful recessive trait in the hybrids.


Explain the haplo-diploid method of sex determination in the honey bee.

Solution: 


Haplo-diploid method of sex determination in the honey bee:

Chapter 3: Inheritance and Variation Balbharati Solutions for Biology 12th Standard HSC Maharashtra State Board

1. In honey bees, the chromosomal mechanism of sex determination is of haplo-diploid type.

2. In this type, the sex of the individual is determined by the number of the set of chromosomes received.

3. Females are diploid (2n=32) and males are haploid (n=16).

4. The female produces haploid eggs (n=16) by meiosis and male produces haploid sperms (n=16) by mitosis.

5. If the egg is fertilized by sperm, the zygote develops into a diploid female (2n=32) (queen and worker) and an unfertilized egg develops into a haploid male (n=16) (Drone) by way of parthenogenesis.

6. The diploid female gets differentiated into either worker or queen bee depending on the food they consume during their development.

7. Diploid larvae which get royal jelly as food develops into queen (fertile female) and other develops into workers (sterile females).

 

What is parthenogenesis?

Solution: 


Parthenogenesis:

The process by which a female produces offspring from unfertilized eggs is known as parthenogenesis.



Long answer type question.


In the answer for inheritance of X-linked genes, Madhav had shown carrier male. His answer was marked incorrect. Madhav was wondering why his marks were cut. Explain the reason.

Solution: 


A male has X and Y chromosomes. The X-linked genes do not have their alleles on Y chromosome. Therefore, for males to suffer from disease only one copy of a defective gene is sufficient. In the inheritance of X-linked genes, females may be carriers because they have two X chromosomes and may carry one normal and another defective gene. This is not possible in the case of males due to the presence of a single X chromosome.


With the help of a neat labelled diagram, describe the structure of chromosome.

Solution: 


Structure of chromosome:

i. Chromosomes are highly condensed and therefore are clearly visible in metaphase stage of cell division.

ii. A typical chromosome consists of two chromatids joined together at centromere also known as primary constriction.

iii. Primary constriction consists of a disk shape plate called kinetochore. During cell division, spindle fibres get attached to the kinetochore.

iv. Apart from primary constriction, some few chromosomes possess additional one or two constrictions called secondary constriction.

v. At secondary constriction I (nucleolar organizer), the nucleolus becomes organized during interphase.

vi. A satellite body (SAT body) is attached at secondary constriction II, in very few chromosomes.

vii. Each chromatid in turn contains a long, unbranched, slender, highly coiled double-stranded DNA thread, called chromonema, extending through the length of the chromatid.

viii. The ends of the chromosome (i.e. chromatids) are known as telomeres.

Structure of Chromosome-

Chapter 3: Inheritance and Variation Balbharati Solutions for Biology 12th Standard HSC Maharashtra State Board



Explain cris-cross inheritance with suitable example.

Solution: 


Criss-cross inheritance can be explained with the help of two examples: colour blindness and haemophilia.

i. Colour blindness:

a. A person suffering from colour blindness cannot differentiate between red and green colours. Both these colours appear grey to the colour blind person.

b. It is caused due to recessive X-linked genes (Xc) which prevent the formation of colour sensitive cells in the retina that are necessary for distinguishing red and green colours.

c. Dominant X linked gene (XC) is necessary for the formation of colour sensitive cells in the retina of eye.

d. The homozygous recessive females (XcXc) and hemizygous recessive male (XcY) are unable to distinguish between red and green colours. The frequency of colour blind women is much less than colour blind men.

e. When a normal man marries a carrier woman, half of their sons may be colour blind, while the remaining half will have normal vision. All their daughters will have normal vision and half of them will be carriers for the disease.

Chapter 3: Inheritance and Variation Balbharati Solutions for Biology 12th Standard HSC Maharashtra State Board

f. If a colour blind male (XcY) marries a female with normal vision (XCXC), then all the offsprings will have normal vision. The sons will have normal vision but daughters will be carriers for the disease. The carriers have normal vision.

Chapter 3: Inheritance and Variation Balbharati Solutions for Biology 12th Standard HSC Maharashtra State Board

ii. Haemophilia (Bleeder’s disease):

a. Haemophilia is X-linked recessive disorder in which blood fails to clot or coagulates very slowly.

b. The genes for normal clotting are dominant over the recessive genes for haemophilia.

c. The person having the recessive gene for haemophilia is deficient in clotting factors (VIII or IX) in blood.

d. Even minor injuries cause continuous bleeding, hence haemophilia is also called as bleeder’s disease.

e. The recessive gene for haemophilia is located on a nonhomologous region of X chromosome.

f. As there is no corresponding allele on Y chromosome to suppress its expression, so men suffer from this disease.

g. Women suffer only when both X chromosomes have recessive genes (alleles).

1. If a haemophilic male (XhY) marries a female with the normal clotting of blood (XX), then all the offsprings will show normal clotting of blood. The sons will have normal clotting of blood, but daughters will be carriers for the disease. The carriers have normal clotting of blood.

Chapter 3: Inheritance and Variation Balbharati Solutions for Biology 12th Standard HSC Maharashtra State Board

2. When carrier woman (XHXh) marries a normal man (XHY), then all the daughters will have normal clotting of blood but half of them will be carriers for the disease. Half the sons will be haemophilic while the remaining will have normal clotting of blood.

Chapter 3: Inheritance and Variation Balbharati Solutions for Biology 12th Standard HSC Maharashtra State Board



What is cris-cross inheritance?

Solution: 


The inheritance of characters from the father to his grandson through his daughter is called criss-cross inheritance. 


Describe the different types of chromosomes.

Solution: 


Following are the four types of chromosomes with respect to the position of the centromere: Acrocentric (j shaped), Telocentric (i shaped), Sub-metacentric (L shaped) and Metacentric (V-shaped).

Chapter 3: Inheritance and Variation Balbharati Solutions for Biology 12th Standard HSC Maharashtra State Board


Biology 12th Standard 

Balbharati Solutions for Biology 12th Standard HSC Maharashtra State Board Chapterwise List - Free

Chapter 1: Reproduction in Lower and Higher Plants

Chapter 2: Reproduction in Lower and Higher Animals

Chapter 3: Inheritance and Variation

Chapter 4: Molecular Basis of Inheritance

Chapter 5: Origin and Evolution of Life

Chapter 6: Plant Water Relation

Chapter 7: Plant Growth and Mineral Nutrition

Chapter 8: Respiration and Circulation

Chapter 9: Control and Coordination

Chapter 10: Human Health and Diseases

Chapter 11: Enhancement of Food Production

Chapter 12: Biotechnology

Chapter 13: Organisms and Populations

Chapter 14: Ecosystems and Energy Flow

Chapter 15: Biodiversity, Conservation and Environmental Issues


Board Paper With Solutions

MARCH 2013, OCTOBER 2013, MARCH 2014, OCTOBER 2014, MARCH 2015, JULY 2015, MARCH 2016, JULY 2016. MARCH 2017, JULY 2017

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