If the sample size for a trial was calculated based on the following assumptions:

- Response rate Group A = 65%
- Response rate Group B = 50%
- Significance level 5%
- Power = 90%
- Objective to show a difference between treatment groups

Which of the following changes to the assumptions would result in the required sample size increasing?

**1)** Changing the Expected Response Rate in Group A to 68% while all other assumptions remain the same

**2)** Changing the Expected Response Rate in Group B to 48% while all other assumptions remain the same

**3)** Changing the Power Level to 80% while all other assumptions remain the same

**Which of the following is correct**